New vaccination strategies coach immune system to make HIV-neutralizing antibodies
HIV circulates in a person's body in many variants that mutate rapidly and escape defensive immune responses. New approaches are needed to develop a broadly effective AIDS vaccine. Credit: © Krasimira Nevenova / Fotolia New approaches that could spur the human body to produce HIV-blocking antibodies have been successful in mice mimicking the human immune system, according to five studies published today in the research journals Cell , Immunity and Science . The results were produced by scientists affiliated with the International AIDS Vaccine Initiative (IAVI); The Scripps Research Institute (TSRI); U.S National Institute of Health's National Institute of Allergy and Infectious Diseases (NIAID); Howard Hughes Medical Institute (HHMI); The Rockefeller University; Ragon Institute of Massachusetts General Hospital, MIT and Harvard; Boston Children's Hospital; Massachusetts Institute of Technolog y...